ABSTRACT
Shilajit [Botanical/Scientific name: Asphaltum] is a bituminous substance found in the lower Himalayan mountains. It is a compact mass of vegetable organic matter composed of a dark gummy matrix thought to be largely the result of humification of the plant Styrax officinalis Linn, and/or Euphorbia royleana Boiss. Shilajit is used as aphrodisiac, rejuvenator, alterative tonic, respiratory stimulant, internal antiseptic, diuretic and lithotriptic. In the current study, we investigated the free radical scavenging effects of hydroalcoholic extract of Shilajit, employing various established in vitro systems, such as the p-carotene-linoleate model system, 1, l-diphenyl-2-picrylhydrazyl [DPPH] and nitric oxide radical scavenging activity. Shilajit showed noticeable inhibitory activity toward p-carotene-linoleate model system, inhibition of DPPH radical and also possessed nitric oxide scavenging activity. The data obtained in the in vitro models clearly establish the free radical scavenging effects of hydroalcoholic extract of Shilajit
ABSTRACT
Various antiseptic creams are available in the market. These preparations tend to gain high viscosity at low temperatures [below 0°C] and it becomes difficult to remove cream from the container in desirable quantity with the tip of the finger or from big containers with the help of scoop. In the present work attempts were made to develop the cold stable antiseptic cream. Essential oils of Sandal and Khas were added in the cream for their antiseptic property